I voted no, I very much doubt she'd make a return. If Jill wasn't still around then she would of replaced her I think, so Chris will always have a partner. As Capcom like having characters in twos, such as Chris and Jill, Leon and Claire etc.
If she was to make a comeback, then i'd ask why hasn't Billy, Carlos, Ashley or Barry had their long awaited comeback, forget Ashley on that matter.
It would be nice to have her as a sub character in future games, so she can have flashback convos with Chris over Wesker etc.